This project presents the Auditory Desensitization and Neuromodulation System (ADNS), an innovative AI-powered headset developed to mitigate the effects of misophonia. The system uses advanced real-time sound filtration and active noise cancellation to selectively suppress triggering sounds such as chewing or breathing without distorting the overall auditory experience. A custom-trained AI model enhances accuracy by identifying and filtering specific stimuli. Real-world testing across diverse environments confirmed the device’s reliability, minimal latency, and potential for scalable personal and clinical applications.